What do we do?

Living Evidence to inform health decisions is a research project focused on knowledge transfer and capacity building that involves the design and evaluation of a model strategy to generate, use and apply tools to help health decisions be based on the most recent evidence thanks to its potential to be constantly updated.

We support health system organizations in charge of developing KT products to inform health decisions, build capacity in innovative and effective tools, as well as support applying the methodology and processes of the rapidly changing evidence synthesis.

Working Group

María Ximena Rojas RN. MSc. PhD

IIB Sant Pau Barcelona, Spain

Gerard Urrutia MD. PhD

IIB Sant Pau Barcelona, Spain

Pablo Alonso MD. PhD

IIB Sant Pau Barcelona, Spain

Gabriel Rada MD

Epistemonikos Foundation, Santiago, Chile.

David Rigau Commas. MD. PhD

Iberoamerican Cochrane Centre Barcelona, Spain

Josefina Bendersky. DDS. MSc

Research Associate - IIB Sant Pau

Camila Ávila. DDS. MSc

Research Associate - Epistemonikos Foundation

Ariadna Auladell. Lic. FP. MSc

Research Associate - IIB Sant Pau

Francisca Verdugo DDS. MSc

Research Associate - Epistemonikos Foundation


The project will be developed in three complementary phases:

The first focused on developing a support and capacity strategy for organizations.

The second and third, focused on meeting the training objective, combine courses, workshops and practices under the principle of “learning by doing”

A set of training workshops will be carried out, aimed at the participants designated by each participating organization. Training will be focused on the processes inherent to generating living evidence based on the Epistemonikos L.OVE platform.

For this project, the Epistemonikos L.OVE platform will be the tool used as part of the strategy to keep the living evidence (i.e. for generating and maintaining the living evidence process).

We support the participating organizations in the development of the Living Evidence synthesis for a group of selected questions, using the “Living Evidence to Inform Health Decisions framework

Project Management Structure

The project is being coordinated from the Institut d’Investigació Biomèdica Sant Pau (IIB Sant Pau) / Clinical Epidemiology and Public Health Service of the Hospital de la Santa Creu i Sant Pau / Iberoamerican Cochrane Center, with the support of the group of researchers from the Epistemonikos Foundation

It has a group of expert methodologist advisers on issues related to living evidence synthesis, development of clinical practice guidelines, and technology evaluations.

Project Management Structure

Group of expert methodologist advisers

Steve McDonald

Senior Research Fellow Monash University, Australia. Co-Director of Cochrane Australia. 

Tari Turner

Associate Professor (Research), Monash University, Australia. Director, Evidence and Methods, National COVID-19 Clinical Evidence Taskforce. Executive Committee, Australian Living Evidence Consortium.

Philippe Ravaud

Director of the INSERM Epidemiology and Biostatistics Research Center. Full professor Faculté de Médecine. Université de Paris, France

Emma McFarlane

Technical Adviser NICE Surveillance programme. London U.K.

Holger Schünemann

Professor of the Department of Health Research Methods, Evidence, and Impact McMaster University in Hamilton, Canada. Director of Cochrane Canada. Director of the McMaster GRADE Centre.

Elie Akl

Associate Professor. Department of Epidemiology and Population Health, American University of Beirut; Director of Clinical Epidemiology Unit at the Clinical Research Institute, American University of Beirut; and Co-Director of the Center for Systematic Reviews of Health Policy and Systems Research (SPARK)


The project is part of a research program led by María Ximena Rojas as the principal investigator, who currently holds an individual fellowship H2020 Marie Curie Action (MSCA-IF-EF-ST #894990)

Research Institute of the Santa Creu i Sant Pau Hospital – Sant Pau Biomedical Research Institute (IIB Sant Pau)

Thanks to the grant of the Programa Estatal de Generación de Conocimiento y Fortalecimiento del Sistema Español, Subprograma estatal de generación de conocimiento, Instituto Carlos III de Madrid, this project is running its secound phase (extention) entitled “Strengthening decision-making capacity in the Spanish Health System through living evidence: An innovative framework” (see the protocol here)