LE-implementation framework

This living evidence implementation framework seeks to support organizations that work in developing evidence synthesis as part of knowledge transfer (KT) products, such as recommendations in clinical practice guidelines (CPG), health technology assessment reports (HTA), structured summaries of evidence (SSE) for institutional and public policies among others,  in the task of incorporating constantly emerging evidence and generating valid and reliable results to inform decision-making.

This implementation framework guide organizations teams to use appropriate criteria for defining which clinical problems (structured into clinical questions) benefit from a constant review of the new evidence, the frequency with which these processes should be carried out, and whether to incorporate the new evidence into the existing synthesis and conclusions of the KT-products which this evidence supports. The framework is divided into four fundamental sections based on the moment in which they must be applied during the evidence synthesis process. Each section poses a series of questions that guide the developers (e.g. technical team) in defining each step of the process.

Section A
What are the problem and its derived questions?

Fill it out once the health problem or question has been identified as potentially relevant for a “living evidence” approach

Section B
Does the question warrant a “living evidence” approach?

Fill it out after running a first pragmatic search of evidence answering the question of interest

Section C
How the “living evidence” synthesis will be carried out?

Fill it out during the planning phase of the evidence synthesis

Section D
Constant monitoring of new evidence (evidence surveillance)

Fill it out each time the evidence is reviewed during monitoring process